The Best CBD Oil for Depression

CBD is a cannabis molecule with a wide range of benefits not just for your body, but also for your mind. Studies have found that it can have mood-boosting effects and relieve anxiety, making it a very beneficial supplement for people who suffer from depression.

In this article, we delve a little deeper into what makes CBD useful for depression. We discuss why the best CBD oil for depression is a good method of delivery, how it actually works, and how to take it for the best results. Finally, we’ll be showing you a selection of products we believe in CBD oils with the right ingredients and potency, as well as all the quality certificates we look for in a CBD product. 

Does CBD oil help with depression?

Yes, or at least the research that has been published so far suggests that it does. According to these studies, CBD can lift up the mood of people with depression, as well as relieve anxiety and improve sleep.

Since depression is a condition with a wide set of symptoms, a molecule like CBD is particularly useful. It does more than just improve your mood; it can also help you relax in your body, give you better sleep, improve your everyday stress, and more. 

CBD alone may not be enough to “fix” your depression, and it’s important to consult a mental health specialist if you experience depressive symptoms. However, we believe that CBD can improve the overall well-being of people with depression, whether or not they are also receiving specialized treatment. 

There are many ways to take the best CBD oil for depression, including oil, cream, capsules, and more. In this article, we’ve chosen to focus on oil because it’s by far the most popular product out there. Not only is it easy to find, it’s also easy to dose, and very affordable in terms of the price per milligram of CBD. 

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How to take the best CBD oil for depression

If you’re thinking of trying out the best CBD oil for depression, you should note that it’s not a one-time dose. To really experience the mood-boosting effects of CBD, you’ll have to commit to taking it on a daily basis. In fact, many people find that they only start to experience the benefits of CBD oil two to three weeks after they start taking it. Some people notice results much faster, but the fact remains that if you make a habit of taking it every day, you’re a lot more likely to see the results you want. 

To take the best CBD oil for depression, place a few drops under your tongue. It’s up to you to determine how much you want to take. People generally get good results with taking anywhere from 15 mg up to 50 mg of CBD each day—which is something that depends on your needs, your age, weight, and gender. Once the best CBD oil for depression is under your tongue, leave it there for a few seconds (a few minutes is ideal) before swallowing. This allows CBD molecules to enter your bloodstream through the sublingual gland, making the method of delivery a lot more efficient. 

Endoca Raw Hemp Oil
1. Endoca Raw CBD and CBDa hemp oil 1,500 mg
This is our first choice for people who experience anxiety alongside depression.


Our first choice for people with depression is this raw hemp oil by European brand Endoca. It contains raw CBD extract, a form of CBD that has been minimally processed and retains a lot more vitamins, minerals, terpenes, and cannabinoids. As well as having a full spectrum of cannabinoids, this product is very rich in CBDa.

CBDa is a molecule found in cannabis, which you don’t usually find in CBD products that have been processed or heated up. Although there isn’t as much research on it as there is on CBD, a few studies show that it affects our serotonin receptors, and has the ability to boost mood and fight anxiety. 

Both the CBD and the CBDa are particularly strong in this product. With 5 mg of CBD per drop, it’s perfect for those who need a higher dose of CBD. If you’re only thinking of taking a few milligrams a day, it can also be good: you’ll only need one or two drops and not a full dropper to get your daily dose!

In terms of quality, it’s a product that has everything we look for: it’s organic and GMO-free, third-party tested, and even sustainable. Make sure to visit Endoca’s website to check out this product’s certificate of analysis if you’re interested; it’s a great way to check for yourself exactly what cannabinoids and terpenes it contains. 


  • Very strong product
  • Pure, raw, minimally processed hemp extract
  • Rich in CBDa


  • Not the best price per milligram of CBD
  • This oil is rarely on offer
CBD Fx Wellness Tincture
2. CBDfx Wellness 2:1 Tincture CBD + CBG
A great product for those looking to try out CBD, the “new CBD.


If you’ve never heard of CBG, don’t worry! This cannabis molecule is one of the rarer ones, and its popularity has only started to grow fairly recently. In this wellness tincture by US brand CBDfx, you’ll find a 2:1 ratio of CBD to CBG. This is a great formulation for people with depression, as CBG and CBD really complement each other when it comes to mental wellness. CBD can have mood-boosting effects, while CBG is even better at relieving anxiety. Taken together, these two molecules can lift your mood up and make you feel more grounded. 

One thing which we really like about this product is that you can get it in four different strengths. The lightest potency available is 500 mg of CBD per bottle, and the strongest is 4,000 mg. For most people with depression, we recommend the two lightest options. That being said, some people do find that they need more, in which case the very high-potency options are perfect.

You won’t be disappointed by the quality of this product. It’s organic and GMO-free, made with hemp that’s grown in the USA. It’s also manufactured using CO2 extraction for greater purity, and is third-party tested. So if you’re looking for a high-quality CBD product that comes in many potencies and contains more, useful cannabis molecules, make sure to give this one a try.


  • Great value for money
  • Contains added terpenes, curcumin, coenzyme Q10
  • High in CBG
  • Four potencies available


  • Not for you if you don’t like the taste of stevia
Joy Organic Premium CBD Oil Tranquil Mint (30mg)
3. Joy Organics Tranquil Mint CBD oil tincture with 225 to 1,350 mg CBD
This is our best pick for those who want a flavored CBD oil.


We know the taste of CBD isn’t to everyone’s liking. This is why we really value products like this Joy Organics CBD oil, which comes in four different flavors options. Get this tincture in a neutral version, or tasting like peppermint, orange, or lemon. All the options are flavored with completely natural and organic essential oils.

The rest of the ingredients in these products are equally safe and natural. It contains broad-spectrum CBD extract, extra virgin olive oil or MCT oil (depending on the flavor) and essential oils of orange, lemon, or peppermint. 

Like all Joy Organics products, it’s made with fully organic ingredients, GMO-free, and third-party tested. It also comes in a dark glass, airtight bottle that helps preserve the quality of the product for longer.

In terms of potency, it’s a product that comes in four strengths ranging from 7.5 mg to 45 mg of CBD per serving. We think that most people with depression will benefit from a lighter dosage of CBD taken regularly, but it might be that you’ll benefit from a higher-potency option. 

If you’re looking for a product with great taste, great quality, and flexible pricing options, this is our first choice. 


  • High-quality, broad-spectrum CBD extract
  • Guaranteed THC-free
  • Four available tastes
  • Four available strengths


  • Price per milligram of CBD is higher than average
  • No international shipping
Charlotte’s Web Max Strength 60mg CBD:mL Oil Tincture
4. Charlotte’s Web Max Strength 60mg CBD/mL Oil Tincture
This strong Charlotte’s Web oil tastes great and packs a serious punch of CBD.


If you’re looking for a high-quality full-spectrum product that comes in a variety of flavors, this Charlotte’s Web oil is perfect for you. Its list of ingredients is very simple: coconut oil, CBD extract, and natural flavorings. 

The main advantage of choosing a full-spectrum product is that the cannabinoids, terpenes, and flavonoids that it contains can strengthen one another. For example, other cannabinoids like CBN or CBG also have anxiety-fighting effects, and terpenes are known to make the effects of CBD stronger.

Like all Charlotte’s Web products, this CBD oil is organic, third-party tested, GMO-free, and made with U.S.-grown hemp. It comes packaged in a high-quality, dark glass dropper bottle. 

In terms of potency, this is definitely one of the strongest products you can find. It contains 60mg of CBD in each 1mL dose, making it ideal for those with more severe depression. It could also be a good option for you if you’ve tried taking CBD for depression before, but haven’t really felt the effects that you wanted to get. 

Coming in at $119.99 for a 30mL, 1,800mg of CBD bottle, it isn’t the most affordable product out there. However, it does offer some exceptional value for money, and can be a great investment if you use CBD on a day to day basis. Get it in three different flavors, chocolate mint, orange blossom, or lemon twist. 


  • Broad-spectrum hemp extract
  • High CBD potency
  • Different flavor options
  • Dark glass dropper bottle


  • No free shipping outside of the U.S

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