The Best Topical CBD Creams for Neuropathy (Nerve Pain) – Pain Relief

To have neuropathy is to experience a shooting or burning pain that is the result of nerve damage. It can sometimes fade when left alone, but the condition can also be chronic. Standard treatments include a course of anticonvulsant and anti-inflammatory drugs that are designed to decrease inflammation and pain. There are also electrical stimulation techniques for calming the nerves and decreasing pain. With that said, we always recommend speaking to a professional.

As CBD is an anti-inflammatory compound, many individuals are turning to CBD creams to control neuropathy pain and inflammation. The CBD compound can be taken in many forms, but most agree that CBD creams are ideal for nerve pain.

You may notice that we only list a few products in this review – this is because they are the best we have used. There is simply no need to recommend sub-par alternatives. This guide is designed to reveal the best CBD creams for nerve pain. All products in this guide are from respectable brands that use high-quality cannabidiol that is derived from hemp. Again, please speak to a health professional if you are experiencing nerve pain. Without further ado, let’s get started.

CBDFx muscle joint cream

1. Muscle & Joint CBD Hemp Cream 500mg/1000mg

For those looking to get fast-acting relief from nerve pain, this water-based cream by CBDfx is a great option


Thanks to its thin formula, the product is easy to apply and can absorb into your skin in a matter of minutes. The compact bottle size makes it a great product to have on hand when neuropathic pain flares up.

As well as containing good amounts of CBD (it comes in 500mg or 1000mg versions), this cream is also formulated with natural ingredients that act as painkillers. Caffeine can have natural pain-relieving effects, and white willow bark extract is one of the oldest painkillers known to man (and the ancestor of aspirin!)

The CBD in this cream is broad-spectrum, meaning that you can get additional benefits from the cannabinoids and terpenes that reinforce and complement the effects of CBD. It’s also certified organic, GMO-free, third party certified, and it’s GMP compliant meaning that the hemp has been extracted following strict quality standards. 

In terms of value for money, this cream offers a great price per milligram of CBD, with a medium concentration that costs $39.99 for 500mg of CBD, and a highly concentrated version that retails for $79.99. When you take into consideration the other natural products it contains, we think it’s a great deal (and have a look, it’s often on sale too!)


  • High potency
  • Contains pain-relieving ingredients like white willow bark
  • Broad-spectrum CBD extract



  • Not suitable for those with aspirin intolerance
  • Contains caffeine


Joy Skin & Body Premium CB Salve

2. Premium CBD Salve 500mg by Joy Organics

This Joys Organic premium CBD salve is a simple and gentle product that can ease nerve pain thanks to its high-quality CBD and fresh essential oils.


It comes in a 1oz jar that contains 500mg of CBD, a medium concentration that works great for daily use. You can also get this cream in a 2oz version that contains double the amount of CBD—which can be ideal for those of you who rely heavily on CBD to relieve nerve pain. 

Like all Joy Organics products, this salve is made with natural ingredients that are organic and gentle on the skin: MCT oil, beeswax, CBD extract, lavender and eucalyptus essential oils. Yes, that’s it! This simple ingredient list is definitely a pro for those who like to know exactly what they are putting on their skin and don’t want any synthetic ingredients. 

As well as giving the cream a pleasant scent, the lavender and eucalyptus essential oils also have pain-relieving properties of their own. In fact, the anti-inflammatory and painkilling properties of these oils have been used to relieve that sort of pain for hundreds of years. So if aromatherapy is also something you’re interested in, don’t hesitate to give this product a try.

Made with organic, third-party tested and U.S-grown hemp, it’s a high-quality CBD product that has everything you need. It doesn’t pretend to use too many fancy ingredients, but it gets the job done. And for those who need CBD daily, we think it’s a great investment. 


  • 100% natural ingredients
  • Comes in different potency options
  • Dark glass container
  • Guaranteed THC-free



  • Strong eucalyptus scent
  • Relatively thick texture which could be hard to spread



3. Elixinol CBD Sports Gel 1000mg

This is a fast-absorbing product that offers good value for money and a serious punch of CBD.


One of our best picks for neuropathic pain is this fast-absorbing, high-potency product by Elixinol. As well as containing CBD, it’s enriched with other botanicals that fight pain naturally. It contains capsaicin, a molecule found in chili peppers, which has pain and inflammation lowering properties. It’s also made with arnica, a flower extract that is one of the oldest forms of pain relief known to man. Finally, it’s formulated with a great range of essential oils, many of which have pain-fighting properties. 

One of the things which we like the most about this product is how easy it is to apply. Unlike a lot of topical CBD products, it doesn’t contain heavy ingredients like cocoa or shea butter. Instead, its gentle moisturizing properties come from plants like aloe vera and witch hazel. This makes it absorb into your skin faster, and without leaving a residue. This combined with its pain-fighting ingredients like capsaicin makes it a great product if you want pain relief you don’t have to wait for.

With 1000mg of CBD for $59.99, it’s a product that offers good value for money, particularly considering the quality of all its ingredients. So if you’re looking for a fast-acting, strong gel that can last you a while, we couldn’t recommend this one more.


  • Contains many pain-fighting ingredients like arnica and capsaicin
  • Strong potency
  • Great price per milligram of CBD
  • Portable format makes it easy to carry with you



  • Little to not moisturizing effects
  • Could take a long time to ship (especially outside of the U.S.)
Endoca Hemp Salve

4. Endoca Hemp Salve 750mg

This thick CBD topical is our best CBD salve for neuropathy.


After testing the majority of CBD products on the market, Endoca’s Hemp Salve is defiantly out favourite. It is a CBD-rich salve that is made from high-quality cannabidiol and a range of nourishing ingredients. In fact, as soon as we opened the tub we were impressed by the beautifully-fresh lemon aroma.

After taking in the scent, we dug our fingers into the salve to get a closer look. Doing this, we soon realized that this product that was thicker, more concentrated consistency when compared to other creams on the market.. In fact, we had to warm the product up in our finger tips before applying.

The salve soaked in well, leaving no greasy residue. Since trying this product, I use this on my elbows and other small joints that get achy from the gym. We would say this is the best topical CBD for neuropathy in concentrated areas.

The tub contains 750mg of CBD, which should provide enough salve for at least a month of regular usage on smaller areas.  It would be the best CBD foot cream for neuropathy.

The product also contains a bunch of nourishing ingredients to keep the skin healthy: CBD (cannabidiol), Coconut Oil, Beeswax, Cannabis Sativa Seed Oil, Citrus Medica Limonum (Lemon) Peel Oil, Citral, Vanilla, Vitamin E.

Endoca ship worldwide, so it doesn’t matter if you’re in the USA or UK, although people from the USA get free delivery when ordering over $74. The salve is currently priced at $64 (or equivalent in your currency), which is fair for a cream that does more than keep you moisturized. You can follow the link below to learn more about the product.


  • Very high potency product
  • The ingredients are 100% natural and food-safe
  • Sustainable brand
  • Fast shipping



  • Difficult to apply to large areas because of its density
  • Not the most affordable product (but great price per milligram of CBD)


CBD Medic Active Sport Pain Relief Ointment

5. Charlotte’s Web Active Sport Pain Relief Ointment

This Charlotte’s Web CBD cream is ideal if you enjoy the cooling, tingling effects of menthol and camphor.


People with neuropathic pain can benefit from using a product such as this one, which combines the pain-relieving effects of CBD with those of menthol and camphor. This Charlotte’s Web ointment is made with 200mg of CBD, 10% camphor, and 15% menthol. It also contains some hydrating oils and fragrant essential oils.

Both camphor and menthol are known for their topical, painrelieving properties. Camhor has relaxing and warming properties, while menthol has a cooling, numbing effect. Put together, the two ingredients fight pain and create a numbing sensation on the skin which helps you feel relief faster. And since 200mg of CBD per 40mg of product is quite a high dose, you won’t need to use a lot of the product to get the relief you want.

In terms of texture, this is a relatively thick ointment that works best for covering small patches of skin. It isn’t very hydrating, but the upside of that is that it also won’t leave any greasy residue on your skin. Finally, it’s scented with natural myrrh, frankincense, and honeysuckle essential oils which give it a rich, earthy smell. 

Like all Charlotte’s Web products, it respects the highest standards of quality: it’s made with CO2-extracted, third-party tested, broad-spectrum CBD and doesn’t contain any synthetic additives. If you’re looking for a strong, dense product with an interesting numbing effect, this is the one for you.


  • Broad-spectrum CBD extract
  • Cooling effect thanks to menthol extract
  • Dark glass container



  • Relatively low CBD potency
Smile CBD Topical CBD Cream for Pain “Rejuvenate” 500mg

6. Smile CBD Topical CBD Cream for Pain “Rejuvenate” 500mg

If you're trying to find a topical CBD cream that's excellent for body pains, this is just one of our best picks.


Manufactured with 500mg of Smile CBD hemp extract per container, it’s a medium-potency CBD cream that’s excellent for aching muscles, aching joints, and any other sort of mild to moderate pain. 

Something we truly like about this cream is the fact that it makes the most of more than simply CBD as a source of pain relief. As an example, it contains active ingredients like arnica as well as menthol, which are known to relieve pain instantaneously when put on the skin. It also has magnesium, a nutrient which is extremely crucial for muscle health and can fight muscle cramps effectively. 

Other ingredients in this CBD cream also deliver on quality. It’s made with hydrating argan oil, avocado oil, as well as cocoa butter. However though they’re really moisturizing, these ingredients do not give the CBD cream a heavy feeling. It continues to be light as well as simple to apply– especially since it is available in a hassle-free bottle with pump head. In general, it is just one of our best-loved options for those of you that want a medium-potency, topical CBD cream for pain relief.


  • Very moisturizing thanks to cocoa butter and avocado oil
  • Contains cooling menthol
  • Made with pain-relieving arnica
  • Transdermal magnesium to support muscle health
  • Comes in an opaque bottle with convenient pump head


  • Container isn’t recyclable
  • Domestic shipping only
Extract Labs CBD - Topical CBD Cream for Muscles 1,500mg Full Spectrum

7. Extract Labs CBD - Topical CBD Cream for Muscles 1,500mg Full Spectrum

If you're searching for a high quality CBD cream with a fresh, cooling feeling, this Extract Labs CBD ointment is a great option.


With 1,500 mg of CBD in a 3-oz jar, it’s a CBD high potency topical that’s certain to relieve even the most extreme pains. We advise it to people with joint inflammation, muscle cramps, period pain, and other pain issues. Its CBD high potency also makes it an excellent choice for individuals that struggle with skin conditions like eczema or psoriasis. 

In its list of ingredients, you’ll see all-natural oils and butters like jojoba oil and shea butter. You’ll also discover soothing arnica and cooling menthol, that make the pain-relieving benefits of this CBD cream even more instant. And for fragrance, Extract Labs CBD work with lavender as well as rosemary essential oils which give this topical CBD cream a fresh and very natural smell. 

It’s manufactured with full spectrum CBD extract, meaning that it also has various other phytocannabinoids and terpenes. The extract itself is certified organic, third party tested cbd, and obtained from non-GMO U.S. hemp. If you’re a veteran, a nurse, or a teacher, you can even profit from Extract Labs CBD’s 50% off solidary discount. And even if not, you’ll be supporting a firm that makes social impact a priority!


  • CBD high potency
  • Full spectrum CBD extract
  • Certified organic
  • Third Party tested CBD
  • Contains pain-relieving menthol and arnica
  • All-natural ingredients


  • Free shipping when you spend $50 or more
MedTerra CBD Reviews - Topical CBD Cream for Pain 500-1000mg

8. MedTerra CBD Reviews - Topical CBD Cream for Pain 500-1000mg

If you're trying to find a high quality CBD cream for pain relief, this one is a wonderful choice.


It comes in 2 strength options of 500 or 1,000 mg of medterra CBD products per jar– which is more than enough for soothing most pain problems. We recommend the lower strength alternative if you struggle with sore muscles or light pain, or the CBD high potency choice for muscle cramps or period cramps, joint problems, or more extreme pain in the back. 

We love the simple fact that this topical CBD cream is made with all-natural ingredients, including soothing aloe vera, moisturizing jojoba oil, and even refreshing peppermint oil. It also has natural pain-relieving components like arnica extract, menthol, as well as rosemary leaf distillate. These are all natural ingredients that have been shown to soothe pain when applied topically. Simply put, they make the benefits of this topical CBD cream even more powerful. 

When it comes to texture, this is a light cream that’s simple to spread onto larger spots of skin. Because of its water-based formula, it soaks up rapidly and will not leave an oily residue on your skin. It’s not a significantly hydrating topical product, but if you’re searching for reliable pain-relief as your main priority, we think you’ll enjoy this product.


  • All-natural ingredients
  • CBD high potency
  • Contains pain-relieving ingredients like menthol and arnica
  • THC-free


  • Contains alcohol
  • Non-recyclable packaging
  • Doesn’t contain other cannabinoids or terpenes
Fabuleaf Full Spectrum Hemp Flower CBD Cream

9. Fabuleaf Full Spectrum CBD Cream 500mg

This natural CBD cream for neuropathy by Fabuleaf has a fresh fragrance and feeling thanks to menthol remove


Searching to buy an easy oil-based CBD cream for neuropathy online that offers a cooling feeling? This Fabuleaf CBD cream for neuropathy pain with 500mg of full-spectrum CBD is the one for you. Like all Fabuleaf products, it’s used organically-grown hemp that’s drawn out without the help of any kind of solvents. The hemp extract has actually the included benefit of being full-spectrum. This implies that none of its cannabinoids and terpenes have been taken out (except for THC.).

Besides 500mg of full-spectrum CBD essence, this cream includes a great variety of all-natural, herb ingredients. It’s made with velvety shea butter and also coconut oil that do a fantastic work of hydrating the skin. It additionally includes cooling menthol, which has pain-relieving residential or commercial properties. Finally, it includes arnica extract, rosemary vital oil, as well as lavender important oil.

With 500mg of CBD in a 1oz container, it’s a tool potency product that’s best for day-to-day usage. We suggest it to anybody who appreciates the cooling feeling of menthol: those with arthritis, muscular tissue aches, sore muscles, duration cramps, etc.


  • Full-spectrum CBD extract
  • Contains moisturizing CBD shea butter
  • Contains pain-relieving menthol
  • Cruelty-free


  • Not unscented 
  • Comes in a clear container
Endoca Hemp Whipped

10. Endoca Whipped Body Butter 1500mg

This is our best CBD cream for neuropathic pain that covers larger areas.


Another product from Endoca, the second CBD topical for neuropathy in this review has a butter-like consistency by combining cannabidiol with a range oils and butters. This consistency is perfect for large areas of nerve pain. In fact, this consistency was the first thing we noticed when we got our hands on this product. Personally, I apply this cream over my lower back after showering and before working out.

Just like the Hemp Salve above, the Whipped Body Butter also contains a load of food-grade ingredients: Shea Butter, Coconut Oil, Palm Oil, Cocoa Seed Butter, Beeswax, Root Starch Vanilla, and Beeswax Vitamin E.

The thing we like about Endoca is that they are a well-respected brand in the CBD industry. They produce third-party reports, which give confidence in the quality of their hemp cannabidiol.

The butter is available in two different sizes, but large 1500mg tub represents the best value for money, and should provide enough CBD to reduce nerve pain for months.


  • The texture makes it very easy to spread
  • Available in two different potencies
  • Simple and natural list of ingredients


  • The sweet vanilla scent could bother some people
  • Endoca rarely offer promotions or discounts


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