The Best CBD Cream for Allergies

When you experience a serious allergic reaction, the best thing to do is to consult a specialist right away. But with minor reactions, it can be harder to know what to do. What should you do if you break out in hives from a mosquito bite, from a new beauty product, from food or even just stress? Chances are, the calming creams that you have at home don’t work, and even natural ingredients like aloe vera and honey aren’t enough to get rid of the itch.

That’s where CBD cream comes in. Products that use the cannabis molecule CBD have the potential to greatly reduce allergic reactions and itchiness thanks to their anti-inflammatory and antipruritic (anti-itch) properties. In this guide, we go over how it works, and what the best products are on the market today for allergic reactions.

Using CBD Cream for Allergies and Hives

There are a couple of things that make CBD cream a great option to provide relief from allergies and hives. First of all, it has anti-inflammatory properties. When we get an allergic reaction, it’s because our inflammation levels are out of balance as a response to a perceived threat. By bringing inflammation levels back to normal, a CBD relief cream can get rid of redness, irritation and itching.

Studies have also shown that CBD can be used to reduce itching for people with various skin conditions. This 2017 review of studies found that cannabinoids like CBD could play an important role in relieving skin disorders, and notably in helping with itchiness. 

Finally, some preliminary studies suggest that CBD could reduce the production of mast cells. Since these cells are responsible for helping our body produce an allergic reaction, reducing them could make us less prone to allergies. 

Let’s sum up the benefits of using CBD Relief Cream for allergic reactions.

cbd cream for allergies

By applying CBD onto your skin, you can reduce inflammation, which will also reduce the appearance of your allergic reaction, the pain that you feel, and the itch. Massaging CBD to the skin could also send signals to your body to produce less mast cells—which could help with hives in the long run. Overall, using CBD cream is a great way to fight allergic reactions in a completely natural way, and experience real relief from the dreaded itch. 

To choose a great quality CBD cream that will help you deal with hives and other allergic symptoms, we’ve put together the guide below with our top picks. All of these products have been selected based on objective quality standards that you can check for yourself.

How to make CBD cream
Endoca Hemp Salve

1. Endoca Hemp Salve 750 mg​

Endoca’s natural, organic CBD salve is our best pick for relieving allergic symptoms. It’s a thick, lemon-and-vanilla-scented cream that contains a high dose of CBD.

At first glance, this salve is rather thick. But after warming it up in between your hands for a few seconds, it becomes much easier to spread and massage into the skin

Made with all natural, organic and food-safe ingredients like hemp seed oil, coconut oil, and lemon peel essential oil, this salve contains only high-quality products that take care of your skin. The natural oils and added vitamin E also make it a very calming and hydrating product, which is perfect when you suffer from skin rashes.

What we like about its thick consistency is that it provides more steady relief from itch and pain. Since it takes longer for your skin to absorb this salve, you’ll experience relief over the course of several hours. This can be a great option if you suffer from an allergic reaction in a small area of skin, and you don’t want to apply cream every 30 minutes! 

At $64 for a tub that contains 750 mg of CBD, this highly dosed product offers very good value for your money. Considering the quality assurance that it comes with (in the form of certificates and documents which you can also find on Endoca’s website), we think it’s one of the best products on the market in its category. 


  • High potency
  • 100% natural ingredients
  • Organic and sustainable product


  • Dense texture which could be hard to spread
  • Not the most affordable product on our list
Endoca Hemp Whipped

2.Endoca Whipped Body Butter

Our second choice for CBD relief cream for allergies and hives is this creamy whipped body butter by Endoca.


Made with natural cocoa butter, shea butter and coconut oil, its smooth consistency makes it ideal to apply on larger areas of skin. 

Like all other Endoca products, it is guaranteed food safe and cruelty free, and it doesn’t contain any artificial preservatives, colors, or fragrances. In fact, we really appreciate its natural vanilla fragrance which is subtle enough to not be noticeable once you’ve massaged it into the skin, but still adds a nice touch to the feel of the product. 

It comes in two different concentrations, with 300 mg or 1,500 mg of CBD. The 300-mg version is a good option if you’re on a budget, if you’re trying out CBD cream for the first time, or if you only suffer from a mild rash. On the other hand, the 1,500-mg version is ideal for those with more irritating allergic reactions and for those who want to get the very best value for money. Considering the quality of its ingredients, it’s hard to beat the price per CBD milligram of the highest- concentrated version. 


  • Very pleasant creamy texture
  • High potency
  • All-natural ingredients


  • Not for you if you dislike sweet scents
  • Endoca have longer shipping times toward the U.S

3. CBD Moisturizing Balm by CBDfx

When you suffer from an allergic reaction, the last thing you want to do is to put irritating products on your skin.

This is why we’ve selected this very simple moisturizing balm by CBDfx. Made with only natural and gentle ingredients, it’s a creamy balm that can really soothe your tight and itchy skin.

It contains ingredients like jojoba oil, shea butter, and evening primrose oil, which are known to calm down irritation. It also has added vitamin E, which can restore some moisture and elasticity where you need it most. More importantly, this product contains no artificial preservatives, colors, or fragrances.

Its calming and invigorating scent comes from a blend of essential oils, including wild orange, lavender, and Roman chamomile. It feels fresh against your skin, and leaves it with a pleasant smell that isn’t too sweet.

And the great thing about it is that you get a full 750mg of CBD in a 2oz jar for just $39.99. In terms of value for money, this is difficult to beat. So if you want an affordable strong product that you know will calm your skin down instantly, this is the one for you.


  • Very pleasant citrus scent
  • Moisturizing ingredients
  • Added vitamin E
  • 100% natural


  • Thick texture that could be hard to apply on the whole body
Joy Cream

4.Premium CBD Cream 250mg by Joy Organics

Most of the CBD products on our list contain essential oils which give them a gentle, pleasant scent.


But if you have very sensitive skin and would rather avoid fragrance altogether, this is the cream for you. This medium-concentration, water-based cream by Joy Organics is made with sensitive skin in mind and is suitable for both face and body.

Unlike most other products on this list, it doesn’t contain any heavy butters like shea or cocoa. Instead, it has ingredients like aloe vera juice, glycerin, and olive oil. This grants it a much lighter texture which could be pleasant if you prefer a cream to a balm. It also means that it’s more suitable for different skin types, including oily and combination skin.

The aloe vera in this product grants it good anti-inflammatory powers, and so do the different terpenes and cannabinoids that it contains. Made with a broad-spectrum CBD extract, this product helps you enjoy the benefits of the entourage effect with a wide range of cannabis compounds. When we know that CBD isn’t the only cannabinoid that can relieve allergic reactions, this is a definite plus. Rest assured though, this product is still guaranteed THC-free! 


  • Water-based, non-heavy texture
  • Moisturizing ingredients
  • High-quality, broad-spectrum hemp extract
  • Pump bottle for ease of use


  • Ingredients aren’t 100% natural
  • Medium-low CBD potency
Elixinol Hemp Balm

5.Elixinol Full-Spectrum Hemp Balm

With a great range of soothing ingredients, this hemp balm by Elixinol is a unique, full-spectrum product that works great on all skin types.


One of the things that makes it particularly well-suited to relieve allergic reactions is that it is rich in calendula flower extract. This is an ingredient that has been used to treat irritation, allergies, and hives for hundreds of years. It has natural soothing properties and is suitable even for the most sensitive skin types.

Being made with a full-spectrum CBD extract means that this product benefits from a lot of other cannabinoids and terpenes that others don’t have. And since many of these cannabis molecules have properties that can relieve allergic reactions, expect to feel greater relief from it. 

In terms of texture, this is a thick and creamy balm that remains relatively easy to apply on large areas of skin. Its scent is a good mix of fresh and floral, with copaiba oil, nerolidol, lemon peel, wintergreen, and bue mallee eucalyptus essential oils. 

If you’re looking for a product with a lot of unique ingredients, great texture, and a full-spectrum of cannabinoids, this is one we highly recommend. It’s even one of the most affordable products on our list, costing $9.99 for its 50mg version, and only $44.99 for the strongest, 500mg version. 


  • Made with full-spectrum hemp extract
  • Long list of natural botanical ingredients
  • Different potency options
  • Dark glass container


  • Strong eucalyptus scent
  • May have longer shipping times than most products

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